Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.45 |
| ▸ | ITGAV | P06756 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401294 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8896265 | 0.83 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8897233 | 0.80 | ITGB3 (0.42) | ITGB3ITGA2BITGAVF2PRSS1 | |
| SCHEMBL8398958 | 0.80 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL8899523 | 0.79 | OXTR (0.37) | ITGB3ITGA2BF2PRSS1TMPRSS15 | |
| SCHEMBL8898789 | 0.74 | F2 (0.39) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8399643 | 0.74 | ITGB3 (0.41) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8402485 | 0.73 | F2 (0.37) | ITGB3ITGA2BF2PRSS1TMPRSS15 | |
| SCHEMBL8401242 | 0.73 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8403456 | 0.71 | ITGB3 (0.40) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |