Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8399866 | 0.97 | SMN1; SMN2 (0.61) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL28145990 | 0.88 | LMNA (0.59) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL28391662 | 0.86 | ALDH1A1 (0.60) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL11196134 | 0.85 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28178151 | 0.85 | ALDH1A1 (0.59) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL11846412 | 0.84 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL8399549 | 0.83 | HDAC3 (0.54) | L3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL28088429 | 0.83 | SMN1; SMN2 (0.56) | L3MBTL1SMN1; SMN2LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8398756 | 0.82 | HDAC3 (0.53) | SMN1; SMN2LMNA | |
| SCHEMBL11197064 | 0.81 | MEN1 (0.60) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |
| EP-0748310-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023128-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-08-31 | — | — | WO | disclosed |