Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5C | P41229 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724532 | 0.85 | HDAC3 (0.39) | ITGB3ITGA2BBMP1 | |
| SCHEMBL7352377 | 0.82 | ITGB3 (0.36) | FOLH1ITGB3ITGA2BBMP1 | |
| SCHEMBL3625944 | 0.80 | CYP2D6 (0.44) | FOLH1ITGB3ITGA2BLMNA | |
| SCHEMBL21724579 | 0.80 | FAAH (0.51) | — | |
| SCHEMBL7443684 | 0.80 | CTSC (0.42) | ITGB3ITGA2BLMNA | |
| SCHEMBL21724577 | 0.79 | FAAH (0.54) | — | |
| SCHEMBL21724159 | 0.79 | FAAH (0.54) | — | |
| SCHEMBL3628190 | 0.79 | KMT2A (0.46) | FOLH1ITGB3ITGA2BLMNA | |
| SCHEMBL21724599 | 0.79 | FAAH (0.54) | — | |
| SCHEMBL3629338 | 0.79 | FOLH1 (0.42) | FOLH1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | claimed |
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |