Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819665 | 0.88 | LMNA (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL10898728 | 0.81 | LMNA (0.36) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL18766559 | 0.79 | LMNA (0.30) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL7960833 | 0.78 | LMNA (0.37) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL28250365 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL337639 | 0.72 | — | — | |
| SCHEMBL27249332 | 0.71 | LMNA (0.32) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL11801978 | 0.71 | TSHR (0.34) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL730154 | 0.70 | LMNA (0.39) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL12841333 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703680-B2 | Lubricating composition containing friction modifier blend | CHEVRON ORONITE COMPANY LLC (US) | 2014-04-22 | — | — | US | disclosed |
| US-20120129743-A1 | LUBRICATING COMPOSITION CONTAINING FRICTION MODIFIER BLEND | CHEVRON ORONITE COMPANY LLC (US) | 2012-05-24 | — | — | US | disclosed |