Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400633 | 0.88 | LMNA (0.36) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL730154 | 0.77 | LMNA (0.39) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL352466 | 0.76 | LMNA (0.38) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL10898728 | 0.74 | LMNA (0.36) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL2924806 | 0.73 | TRPV3 (0.34) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL12880706 | 0.73 | — | — | |
| SCHEMBL26716230 | 0.73 | TDP1 (0.33) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL6842488 | 0.72 | LMNA (0.35) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL7960833 | 0.71 | LMNA (0.37) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| Hydrochloric Acid SCHEMBL28006865 | 0.71 | ABCC3 (0.36) | LMNAKDM4ECNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5009880-A | Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss | L'OREAL (FR) | 1991-04-23 | — | — | US | disclosed |
| US-4719099-A | ANIONIC AND CATIONIC | L'OREAL (FR) | 1988-01-12 | — | — | US | disclosed |
| US-4445521-A | ANIONIC AND CATIONIC POLYMER COMBINATION | L'OREAL (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4240450-A | HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS | L'OREAL (FR) | 1980-12-23 | — | — | US | disclosed |