Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395485 | 0.90 | SMN1; SMN2 (0.34) | AKR1B1LMNA | |
| SCHEMBL8399252 | 0.88 | AKR1B1 (0.36) | AKR1B1HDAC6LMNAGAA | |
| SCHEMBL8396039 | 0.85 | AKR1A1 (0.42) | AKR1B1AKR1A1 | |
| SCHEMBL8399211 | 0.85 | AKR1B1 (0.33) | AKR1B1HDAC6POLBTSHR | |
| SCHEMBL8397943 | 0.85 | AKR1B1 (0.38) | AKR1B1HDAC6LMNAGAAPOLB | |
| SCHEMBL8396280 | 0.84 | AKR1B1 (0.40) | AKR1B1HDAC6AKR1A1 | |
| SCHEMBL8400418 | 0.83 | RAB9A (0.40) | AKR1B1 | |
| SCHEMBL8397720 | 0.82 | AKR1B1 (0.38) | AKR1B1HDAC6AKR1A1LMNAPOLB | |
| SCHEMBL8400716 | 0.82 | AKR1B1 (0.38) | AKR1B1HDAC6LMNAPOLB | |
| SCHEMBL8395838 | 0.81 | AKR1B1 (0.45) | AKR1B1AKR1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |