Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 4/20 | 0.37 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400759 | 0.89 | GLA (0.44) | GLATSHRALOX12NPSR1HSD17B10 | |
| SCHEMBL8397200 | 0.84 | TSHR (0.44) | GLATSHRALOX12NPSR1HSD17B10 | |
| SCHEMBL8400776 | 0.84 | ALOX5 (0.43) | GLATSHRALOX12HSD17B10KMT2A | |
| SCHEMBL8401630 | 0.81 | GLA (0.39) | GLATSHRALOX12NPSR1HSD17B10 | |
| SCHEMBL8401653 | 0.78 | RARB (0.51) | GLAGAARARBRARGPTGDR | |
| SCHEMBL7786437 | 0.77 | RARB (0.48) | GLATSHRALOX12NPSR1HSD17B10 | |
| SCHEMBL13057610 | 0.77 | CYP3A4 (0.47) | GLAHSD17B10MEN1KMT2ATP53 | |
| SCHEMBL8399068 | 0.76 | TSHR (0.41) | GLATSHRALOX12NPSR1HSD17B10 | |
| SCHEMBL7940089 | 0.75 | TSHR (0.46) | GLATSHRALOX12NPSR1HSD17B10 | |
| SCHEMBL7933771 | 0.74 | RARB (0.39) | GLATSHRALOX12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5889095-A | OXYGEN AND HEAT RESISTANCE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |