Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | RARG | P13631 | 3/20 | 0.51 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401580 | 0.84 | RARA (0.56) | RARBRARGRARANR1H2NR1H3 | |
| SCHEMBL8401696 | 0.84 | RARB (0.48) | RARBRARGRARAPTPN1ACHE | |
| SCHEMBL252281 | 0.81 | RARB (0.49) | RARBRARGRARACYP3A4KDM4E | |
| SCHEMBL8400865 | 0.80 | RARB (0.44) | RARBRARGRARAPTPN11PTGDR | |
| SCHEMBL8397200 | 0.79 | TSHR (0.44) | RARBRARGRARANR1H2NR1H3 | |
| SCHEMBL8400747 | 0.78 | GLA (0.46) | RARBRARGRARANR1H2NR1H3 | |
| SCHEMBL14357615 | 0.78 | ESR1 (0.49) | CYP3A4ACHEESR1PGRCHRM2 | |
| SCHEMBL8401630 | 0.76 | GLA (0.39) | RARBRARGRARANR1H2NR1H3 | |
| SCHEMBL12418593 | 0.76 | RXRA (0.58) | RARBRARGRARANR1H2NR1H3 | |
| SCHEMBL7933771 | 0.74 | RARB (0.39) | RARBRARGRARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |