SCHEMBL7933771

SCHEMBL7933771

COc1c(C)cc(OC(C)=O)cc1C1(C)CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.39
RARG P13631 4/20 0.39
RARA P10276 3/20 0.39
ALOX5 P09917 2/20 0.36
ACHE P22303 1/20 0.35
ESR1 P03372 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CHRM1 P11229 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A3 Q01959 1/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8401581 0.86 ACHE (0.39) RARBRARGRARAACHEESR1
SCHEMBL8400776 0.85 ALOX5 (0.43) RARBRARGRARAALOX5TUBB4A
SCHEMBL8397200 0.83 TSHR (0.44) RARBRARGRARAACHEESR1
SCHEMBL8401561 0.83 RARB (0.37) RARBRARGRARAALOX5TUBB4A
SCHEMBL8397568 0.82 RARB (0.34) RARBRARGRARAALOX5TSHR
SCHEMBL8432818 0.81 OPRM1 (0.35) RARBRARGRARAPTGDRPTGDR2
SCHEMBL7794974 0.78 RARB (0.49) RARBRARGRARAPTGDRPTGDR2
SCHEMBL8401580 0.77 RARA (0.56) RARBRARGRARAACHETUBB4A
SCHEMBL8400764 0.75 RARB (0.37) RARBRARGRARAALOX5ACHE
SCHEMBL7794887 0.75 PTGDR (0.43) RARBRARGRARATSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed