Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RARG | P13631 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399246 | 0.85 | GLA (0.47) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL8399071 | 0.84 | GLA (0.40) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL8400766 | 0.84 | PTGDR (0.36) | TSHRGLAALOX12TP53AKR1C3 | |
| SCHEMBL8595049 | 0.83 | GLA (0.43) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL8400772 | 0.81 | GLA (0.46) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL8401328 | 0.81 | GLRA3 (0.36) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL7786437 | 0.78 | RARB (0.48) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL8401697 | 0.78 | RARB (0.50) | TSHRMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL7940089 | 0.76 | TSHR (0.46) | TSHRGLAALOX12NPSR1MEN1 | |
| SCHEMBL7941331 | 0.74 | GLA (0.44) | TSHRGLAALOX12NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |