Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 2/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | CDC42 | P60953 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397573 | 0.83 | RARA (0.54) | RARBRARGRARAPTGS2PTGS1 | |
| SCHEMBL8397554 | 0.81 | RARB (0.45) | RARBRARGRARAPTGS2PTPN11 | |
| SCHEMBL8399071 | 0.80 | GLA (0.40) | RARBRARGRARAPTGS2PTGS1 | |
| SCHEMBL7933778 | 0.80 | RARB (0.45) | RARBRARGRARAPTGS1PTPN11 | |
| SCHEMBL11457396 | 0.78 | PTGS2 (0.47) | RARBPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL8400760 | 0.78 | TSHR (0.44) | RARBRARGRARAPTGS2PTGS1 | |
| SCHEMBL8401328 | 0.77 | GLRA3 (0.36) | RARBRARGRARAPTGS2PTGS1 | |
| SCHEMBL6143601 | 0.75 | RXRA (0.64) | RARBRARGRARAPTGS2PTGS1 | |
| SCHEMBL3809004 | 0.75 | RARB (0.74) | RARBRARGRARAPTGS2PTPN11 | |
| SCHEMBL6143604 | 0.75 | RXRA (0.64) | RARBRARGRARAPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |