Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CDC42 | P60953 | 1/20 | 0.35 |
| ▸ | RAC1 | P63000 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400690 | 0.86 | RARA (0.33) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL8401582 | 0.85 | AKR1C3 (0.39) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL7942419 | 0.84 | PTGDR (0.34) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL8400760 | 0.84 | TSHR (0.44) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL8400785 | 0.82 | RARA (0.33) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL8400789 | 0.82 | RARB (0.35) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL7786557 | 0.80 | RARB (0.47) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL7792167 | 0.78 | PTGDR (0.43) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL8397573 | 0.76 | RARA (0.54) | PTGDRPTGDR2RARBRARGRARA | |
| SCHEMBL8400776 | 0.76 | ALOX5 (0.43) | PTGDRPTGDR2RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |