Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.68 |
| ▸ | HTR2C | P28335 | 12/20 | 0.47 |
| ▸ | HTR1D | P28221 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 7/20 | 0.47 |
| ▸ | HTR2B | P41595 | 7/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797256 | 0.81 | MTNR1A (1.00) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8169091 | 0.77 | MTNR1A (0.63) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| SCHEMBL8169118 | 0.77 | MTNR1A (0.80) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| SCHEMBL8162658 | 0.77 | MTNR1A (0.80) | MTNR1AHTR2CMTNR1B | |
| SCHEMBL8173300 | 0.76 | MTNR1A (0.78) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL8169452 | 0.76 | MTNR1A (0.62) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| SCHEMBL8170080 | 0.76 | MTNR1A (0.78) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| SCHEMBL8169375 | 0.75 | MTNR1A (0.77) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| SCHEMBL8175008 | 0.75 | MTNR1A (0.77) | MTNR1AHTR2CHTR1DHTR1AHTR2A | |
| SCHEMBL8401104 | 0.74 | MTNR1A (0.76) | MTNR1AHTR2CHTR1DHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | claimed |
| US-5998461-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-12-07 | — | — | US | disclosed |