Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.45 |
| ▸ | CETP | P11597 | 8/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397396 | 0.88 | SIGMAR1 (0.38) | SIGMAR1CETPGRM2GRIN2B | |
| SCHEMBL8401133 | 0.81 | SIGMAR1 (0.40) | SIGMAR1CETPGRM2 | |
| SCHEMBL6728351 | 0.77 | SIGMAR1 (0.67) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7208622 | 0.76 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL8198033 | 0.72 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL27527832 | 0.71 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL27481906 | 0.70 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL8397395 | 0.69 | SIGMAR1 (0.40) | SIGMAR1CETPGRM2 | |
| SCHEMBL6720322 | 0.69 | MAPT (0.47) | SIGMAR1 | |
| SCHEMBL6728347 | 0.69 | SIGMAR1 (0.43) | SIGMAR1CETPGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | claimed |