Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 5/20 | 0.35 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.33 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401135 | 0.88 | SIGMAR1 (0.45) | SIGMAR1CETPGRIN2BGRM2 | |
| SCHEMBL8397395 | 0.80 | SIGMAR1 (0.40) | SIGMAR1DDR1CETPUSP28USP25 | |
| SCHEMBL6719823 | 0.76 | SIGMAR1 (0.58) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7203647 | 0.75 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL8401133 | 0.69 | SIGMAR1 (0.40) | SIGMAR1DDR1CETPGRM2 | |
| SCHEMBL6728351 | 0.67 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL6716829 | 0.67 | ALDH1A1 (0.45) | SIGMAR1 | |
| SCHEMBL6719821 | 0.67 | SIGMAR1 (0.40) | SIGMAR1DDR1CETPUSP28USP25 | |
| SCHEMBL27427344 | 0.66 | SIGMAR1 (0.42) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7208622 | 0.66 | SIGMAR1 (0.69) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |