Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 6/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401133 | 0.88 | SIGMAR1 (0.40) | SIGMAR1DDR1CETPALDH1A1GAA | |
| SCHEMBL8397396 | 0.80 | SIGMAR1 (0.38) | SIGMAR1DDR1CETPHDAC8USP28 | |
| SCHEMBL6719821 | 0.76 | SIGMAR1 (0.40) | SIGMAR1DDR1CETPHDAC8USP28 | |
| SCHEMBL6716829 | 0.76 | ALDH1A1 (0.45) | SIGMAR1ALDH1A1GAAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL7203642 | 0.75 | SIGMAR1 (0.41) | SIGMAR1DDR1CETPHDAC8USP28 | |
| SCHEMBL8401135 | 0.69 | SIGMAR1 (0.45) | SIGMAR1CETPGRM2 | |
| SCHEMBL6726814 | 0.68 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTHPGDALOX15 | |
| SCHEMBL6728347 | 0.67 | SIGMAR1 (0.43) | SIGMAR1CETPALDH1A1GAAMAPT | |
| SCHEMBL6719823 | 0.67 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL27427343 | 0.66 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |