SCHEMBL8401173

SCHEMBL8401173

O=C(O)c1ccc2c(=O)c3ccccc3sc2c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HCRTR1 O43613 2/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
PRNP P04156 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
MCL1 Q07820 1/20 0.41
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HPGD P15428 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10727902 0.83 LMNA (0.46) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL300219 0.83 ALDH1A1 (0.48) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL29589251 0.83 ALDH1A1 (0.48) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL31626799 0.83 ALDH1A1 (0.48) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL28533855 0.81 MAPT (0.47) MAPTALDH1A1HCRTR1LMNAPOLB
Ammonia Solution, Strong SCHEMBL30382110 0.81 MAPT (0.47) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL10941770 0.81 LIMK1 (0.46) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL18078283 0.81 ALDH1A1 (0.47) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL10731729 0.79 ALDH1A1 (0.43) MAPTALDH1A1HCRTR1LMNAPOLB
SCHEMBL9811801 0.79 MAOB (0.50) MAPTALDH1A1HCRTR1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962189-A Photosensitive composition containing photosensitive polyamide and thiazoline photoinitiator and negative working photosensitive element KODAK POLYCHROME GRAPHICS LLC (US) 1999-10-05 US disclosed
US-4681950-A PHOTOSENSITIZERS CIBA-GEIGY CORPORATION (US) 1987-07-21 US disclosed
US-4585876-A PHOTOSENSITIZERS CIBA-GEIGY CORPORATION (US) 1986-04-29 US disclosed
US-4560643-A BLEND OF AROMATIC KETONE, POLYMER, AND GROUP IB OR EIGHT METAL SALT CIBA GEIGY CORPORATION (US) 1985-12-24 US disclosed