SCHEMBL9811801

SCHEMBL9811801

O=C(O)c1ccc2sc3ccccc3c(=O)c2c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
MAOA P21397 1/20 0.50
MAPT P10636 6/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
HPGD P15428 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
PRNP P04156 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 3/20 0.43
POLB P06746 3/20 0.43
GAA P10253 1/20 0.43
KDM4E B2RXH2 3/20 0.43
MCL1 Q07820 2/20 0.41
HCRTR1 O43613 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87423 0.89 PRNP (0.48) MAOBMAOAMAPTHPGDCYP1A2
SCHEMBL8440726 0.84 MAPT (0.52) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL16929704 0.84 MCL1 (0.50) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL2021523 0.83 MAOA (0.50) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL28910311 0.82 MAOB (0.48) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL28824618 0.81 MAOA (0.49) MAOBMAOAMAPTNPC1RAB9A
Hydrogen Sulfide SCHEMBL28044841 0.79 MAOA (0.48) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL8401173 0.79 MAPT (0.44) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL8663885 0.78 MAPT (0.44) MAOBMAOAMAPTNPC1RAB9A
SCHEMBL10845561 0.78 MAOA (0.44) MAOBMAOAMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503901-B A kind of thioxanthone dicarboxylic acid diamides and its preparation method and application 广州纽楷美新材料科技有限公司 2018-10-19 CN claimed
CN-105503901-A Thioxanthone dicarboamide compound and preparing method and application thereof HE MINGHUI 2016-04-20 CN claimed
US-5069999-A PRESENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 1991-12-03 US claimed
WO-1990009622-A1 LITHOGRAPHIC PRINTING PLATE COOKSON GRAPHICS PLC (GB) 1990-08-23 WO claimed
CN-105503901-B A kind of thioxanthone dicarboxylic acid diamides and its preparation method and application 广州纽楷美新材料科技有限公司 2018-10-19 CN disclosed
CN-105503901-B A kind of thioxanthone dicarboxylic acid diamides and its preparation method and application 广州纽楷美新材料科技有限公司 2018-10-19 CN disclosed
CN-105503901-B A kind of thioxanthone dicarboxylic acid diamides and its preparation method and application 广州纽楷美新材料科技有限公司 2018-10-19 CN disclosed
CN-105503901-A Thioxanthone dicarboamide compound and preparing method and application thereof HE MINGHUI 2016-04-20 CN disclosed
US-5069999-A PRESENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 1991-12-03 US disclosed
US-4764584-A Radiation-sensitive polycondensates, their preparation, material coated therewith and the use thereof CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed
US-4714669-A POLYAMIDES, POLYESTERS, OR POLYESTER AMIDES CIBA-GEIGY CORPORATION (US) 1987-12-22 US disclosed