Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916963 | 0.71 | ITGB3 (0.51) | MAPTGAAEGFRALDH1A1NPC1 | |
| SCHEMBL7916970 | 0.71 | ITGB3 (0.51) | MAPTGAAEGFRALDH1A1NPC1 | |
| SCHEMBL8636756 | 0.69 | MAPT (0.48) | MAPTGAAMTNR1AEGFRALDH1A1 | |
| SCHEMBL8636753 | 0.69 | MAPT (0.48) | MAPTGAAMTNR1AEGFRALDH1A1 | |
| SCHEMBL8636746 | 0.69 | MAPT (0.48) | MAPTGAAMTNR1AEGFRALDH1A1 | |
| SCHEMBL8503077 | 0.69 | ITGB3 (0.61) | ITGB3ITGAV | |
| SCHEMBL5152873 | 0.68 | GAA (0.57) | MAPTGAAMTNR1AEGFRITGB3 | |
| Hydrochloric Acid SCHEMBL9544373 | 0.67 | GAA (0.56) | MAPTGAAMTNR1AEGFRITGB3 | |
| SCHEMBL1389876 | 0.65 | HTR2A (0.55) | EGFRSMN1; SMN2CYP1A2 | |
| SCHEMBL4420851 | 0.65 | ALDH1A1 (0.74) | MAPTGAAALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | claimed |
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |