Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PARK7 | Q99497 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395503 | 0.80 | ALDH1A1 (0.37) | CACNA1GCACNA1HCACNA1IOPRM1SIGMAR1 | |
| SCHEMBL8402368 | 0.79 | PARP1 (0.33) | CACNA1GCACNA1HCACNA1IOPRM1SIGMAR1 | |
| SCHEMBL8398839 | 0.77 | PARP1 (0.41) | ALDH1A1PARP1PARP2MAPTLMNA | |
| SCHEMBL8402381 | 0.74 | ALDH1A1 (0.33) | PARK7ALDH1A1PARP1PARP2MAPT | |
| SCHEMBL8402387 | 0.73 | MAPT (0.37) | ALDH1A1MAPTLMNAKDM4EPOLB | |
| SCHEMBL8402362 | 0.73 | PARP1 (0.40) | CACNA1GCACNA1HCACNA1IOPRM1PARK7 | |
| SCHEMBL7401018 | 0.72 | ITGB3 (0.43) | CACNA1GCACNA1HCACNA1IALDH1A1MAPT | |
| SCHEMBL8398963 | 0.69 | ALDH1A1 (0.35) | PARK7ALDH1A1ALDH2ALDH3A1MAPT | |
| SCHEMBL7397343 | 0.67 | ITGB3 (0.43) | CACNA1GCACNA1HCACNA1IITGB3ITGA2B | |
| SCHEMBL8518520 | 0.67 | MAPT (0.39) | ALDH1A1MAPTLMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | claimed |
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |