Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518279 | 0.87 | AKT1 (0.37) | RAB9ANPC1KMT2AALDH1A1TP53 | |
| SCHEMBL7397295 | 0.73 | RAB9A (0.39) | MAPTMIFRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7395503 | 0.68 | ALDH1A1 (0.37) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8401237 | 0.67 | CACNA1G (0.35) | MAPTSMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL8518880 | 0.66 | NAMPT (0.45) | KMT2AALDH1A1MEN1 | |
| SCHEMBL12979794 | 0.65 | MAPT (0.76) | MAPTMIFRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6423387 | 0.65 | MAPT (0.76) | MAPTMIFRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3266677 | 0.65 | MAPT (0.76) | MAPTMIFRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6444624 | 0.63 | MAPT (0.72) | MAPTMIFRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8518521 | 0.62 | RAB9A (0.41) | MAPTMIFRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |