Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897377 | 0.91 | ITGB3 (0.42) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8897079 | 0.87 | PARP1 (0.39) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8401220 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8518880 | 0.81 | NAMPT (0.45) | PARP1PARP2 | |
| SCHEMBL8398946 | 0.73 | ITGB3 (0.44) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8401242 | 0.70 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8398823 | 0.69 | ITGB3 (0.39) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8398958 | 0.69 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL8398839 | 0.67 | PARP1 (0.41) | ITGB3ITGA2BITGAVPARP1PARP2 | |
| SCHEMBL8401294 | 0.67 | ITGB3 (0.46) | ITGB3ITGA2BITGAVPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | claimed |
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |