Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401265 | 0.87 | ITGB3 (0.44) | PARP1PARP2BDKRB2ITGB3ITGA2B | |
| SCHEMBL8518880 | 0.80 | NAMPT (0.45) | PARP1PARP2MTNR1AMTNR1BCACNA1G | |
| SCHEMBL8897377 | 0.79 | ITGB3 (0.42) | PARP1PARP2ITGB3ITGA2BITGAV | |
| SCHEMBL8401220 | 0.75 | ITGB3 (0.43) | PARP1PARP2ITGB3ITGA2BITGAV | |
| SCHEMBL8897087 | 0.70 | ALDH1A1 (0.35) | USP2ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL8398839 | 0.69 | PARP1 (0.41) | PARP1PARP2ITGB3ITGA2BITGAV | |
| SCHEMBL7395731 | 0.69 | PARP1 (0.39) | PARP1PARP2ITGB3ITGA2BITGAV | |
| SCHEMBL8402368 | 0.66 | PARP1 (0.33) | PARP1PARP2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL8402362 | 0.63 | PARP1 (0.40) | PARP1PARP2BDKRB2ITGB3ITGA2B | |
| SCHEMBL8398946 | 0.60 | ITGB3 (0.44) | PARP1PARP2ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |