Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26292325 | 0.81 | DGAT1 (0.39) | DGAT1ALDH1A1TET2RECQL | |
| SCHEMBL8783129 | 0.81 | PKM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7428244 | 0.77 | DGAT1 (0.47) | GAADGAT1TET2RECQL | |
| SCHEMBL15806772 | 0.76 | DGAT1 (0.39) | DGAT1ALDH1A1 | |
| SCHEMBL2896418 | 0.75 | GAA (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL13123498 | 0.74 | TSHR (0.39) | DGAT1 | |
| SCHEMBL26292326 | 0.74 | ALDH1A1 (0.36) | MGAMGAASIMGAM2DGAT1 | |
| SCHEMBL31580967 | 0.73 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL25657473 | 0.73 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL759391 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977027-A | NITROGEN CONTAINING CYCLIC COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5834401-A | WIDE VARIETY OF NITROGEN CONTAINING HETEROCYCLES, CLAIMED COMPOUND IS A PIPERIDONE DERIVATIVE OF ISOBUTYRAMIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0747352-A1 | CYCLIC NITROGENOUS COMPOUND AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-12-11 | — | — | EP | disclosed |