Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952070 | 0.82 | KIF11 (0.39) | KIF11NOTUMERN1CA1CA2 | |
| SCHEMBL8401304 | 0.82 | KIF11 (0.42) | KIF11ERN1 | |
| SCHEMBL8404988 | 0.81 | ALDH1A1 (0.38) | KIF11NOTUMCA1CA2CA9 | |
| SCHEMBL8401545 | 0.81 | KIF11 (0.34) | KIF11NOTUMERN1CA1CA2 | |
| SCHEMBL1015538 | 0.78 | KIF11 (0.39) | KIF11NOTUMERN1CA1CA2 | |
| SCHEMBL671603 | 0.77 | ERN1 (0.35) | KIF11NOTUMERN1CA1CA2 | |
| SCHEMBL30361071 | 0.76 | CA1 (0.43) | ERN1CA1CA2CA5ACA9 | |
| SCHEMBL6900813 | 0.75 | ERN1 (0.45) | ERN1MEN1KMT2A | |
| SCHEMBL23121413 | 0.74 | KIF11 (0.42) | KIF11 | |
| SCHEMBL6849157 | 0.74 | KIF11 (0.40) | KIF11ERN1MEN1KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977414-A | 2,3-Dihalogeno-6-trifluoromethylbenzene derivatives and processes for the preparation thereof | NIPPON SODA CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0881207-A1 | 2,3-DIHALOGENO-6-TRIFLUOROMETHYLBENZENE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NIPPON SODA CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |