SCHEMBL8401481

SCHEMBL8401481

NC1=CC=CC(=Cc2ccccc2)C1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
CYP19A1 P11511 1/20 0.32
AKT1 P31749 1/20 0.32
AKT2 P31751 1/20 0.32
AKT3 Q9Y243 1/20 0.32
MIF P14174 1/20 0.32
F3 P13726 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HTT P42858 1/20 0.31
PIM1 P11309 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11099093 0.74
Methylamine SCHEMBL28226585 0.72 ALDH1A1 (0.35) CYP1A2AKT1AKT2AKT3F3
SCHEMBL6745371 0.71 ALDH1A1 (0.37) CYP1A2MAOAMAOBAKT1AKT2
Alcohol SCHEMBL28228419 0.68 TRPA1 (0.34) MAOBALDH1A1
SCHEMBL28066368 0.68 CYP1A2 (0.44) CYP1A2MAOAMAOBMIFF3
SCHEMBL8401484 0.67 CYP1A2 (0.33) CYP1A2MAOAMAOBCYP19A1F3
SCHEMBL11034824 0.66 CYP1B1 (0.35) CYP1A2MAOAMAOBAKT1AKT2
SCHEMBL9315601 0.64 PARP1 (0.36) CYP1A2MAOAMAOBALDH1A1
SCHEMBL6836753 0.64 AKT1 (0.42) CYP1A2MAOAMAOBCYP19A1AKT1
SCHEMBL22471741 0.64 CYP1A2 (0.34) CYP1A2MAOAMAOBMIFF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985012-A SELF-POLISHING PAINT COMPRISING ANTIFOULING AGENT AND RESIN VEHICLE COMPRISING VINYL POLYMER HAVING PRIMARY AMINE PENDANT GROUPS BOUND BY REACTION WITH PENDANT CARBONYL GROUPS NIPPON PAINT CO., LTD. (JP) 1999-11-16 US disclosed