SCHEMBL8401580

SCHEMBL8401580

COc1ccc(OC(C)=O)cc1C1(C)CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.56
RARB P10826 2/20 0.56
RARG P13631 2/20 0.56
PTGDR Q13258 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.45
NR1H2 P55055 2/20 0.42
NR1H3 Q13133 2/20 0.42
LMNA P02545 2/20 0.42
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8397572 0.85 RARA (0.53) RARARARBRARGPTGDRPTGDR2
SCHEMBL8401653 0.84 RARB (0.51) RARARARBRARGPTGDRPTGDR2
SCHEMBL8401556 0.81 RARA (0.49) RARARARBRARGPTGDRPTGDR2
SCHEMBL8430349 0.80 RARA (0.48) RARARARBRARGPTGDRPTGDR2
SCHEMBL7683179 0.80 RARB (0.66) RARARARBRARGPTGDRPTGDR2
SCHEMBL5827950 0.78 RARA (0.50) RARARARBRARGPTGDRPTGDR2
SCHEMBL7689383 0.77 RARB (0.77) RARARARBRARGPTGDRPTGDR2
SCHEMBL9493357 0.77 RARB (0.65) RARARARBRARGPTGDRPTGDR2
SCHEMBL7933771 0.77 RARB (0.39) RARARARBRARGPTGDRPTGDR2
Hydrochloric Acid SCHEMBL9738342 0.76 RARB (0.75) RARARARBRARGPTGDRPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed