Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986073 | 0.79 | EPHX2 (0.36) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL8843240 | 0.75 | SIGMAR1 (0.41) | — | |
| SCHEMBL4982302 | 0.74 | EPHX2 (0.37) | PNMTNPC1RAB9A | |
| SCHEMBL4982318 | 0.73 | SIGMAR1 (0.39) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL8401612 | 0.71 | KDM4E (0.35) | — | |
| SCHEMBL4982722 | 0.71 | NPC1 (0.50) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL17710462 | 0.70 | PNMT (0.45) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL4984321 | 0.69 | NPC1 (0.51) | PNMTNPC1RAB9A | |
| SCHEMBL4393647 | 0.67 | PNMT (0.42) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL1477601 | 0.67 | PNMT (0.52) | PNMTHTR7HTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |