SCHEMBL8401751

SCHEMBL8401751

CCN(Cc1ccc(Cl)nc1)C(=O)NSC

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
LMNA P02545 1/20 0.39
ATM Q13315 1/20 0.38
FAAH O00519 1/20 0.37
MAPT P10636 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
QPCT Q16769 1/20 0.36
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
DGAT1 O75907 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7661984 0.84 ALDH1A1 (0.37) ALDH1A1RAB9ALMNAQPCTKDM4E
SCHEMBL7657367 0.84 ALDH1A1 (0.44) ALDH1A1RAB9ANPC1KMT2AMEN1
SCHEMBL15010610 0.76 ALDH1A1 (0.48) ALDH1A1RAB9ANPC1KMT2AMEN1
SCHEMBL7667959 0.76 KMT2A (0.46) ALDH1A1RAB9ANPC1KMT2AMEN1
SCHEMBL7664499 0.75 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL7664495 0.75 ALDH1A1 (0.38) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL7669297 0.75 KMT2A (0.39) ALDH1A1KMT2AMEN1LMNAMAPT
SCHEMBL13513193 0.74 ALDH1A1 (0.39) ALDH1A1RAB9ANPC1KMT2AMEN1
SCHEMBL8401753 0.74 MAPT (0.43) ALDH1A1RAB9ANPC1KMT2AMEN1
SCHEMBL29494823 0.74 ALDH1A1 (0.43) ALDH1A1RAB9ANPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed