SCHEMBL7657367

SCHEMBL7657367

CSNC(=O)N(C)Cc1ccc(Cl)nc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
RAB9A P51151 3/20 0.41
NPC1 O15118 1/20 0.41
AGTR2 P50052 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
DGAT1 O75907 1/20 0.37
FAAH O00519 1/20 0.36
MTOR P42345 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8401751 0.84 ALDH1A1 (0.43) ALDH1A1RAB9ANPC1MEN1KMT2A
SCHEMBL7658385 0.83 MMP2 (0.38) RAB9ANPC1MTOR
SCHEMBL7685869 0.83 MMP2 (0.38) RAB9ANPC1MTOR
SCHEMBL7666494 0.81 RAB9A (0.57) ALDH1A1RAB9ANPC1MAPTHTT
SCHEMBL3326164 0.79 ALDH1A1 (0.51) ALDH1A1RAB9ANPC1AGTR2MEN1
SCHEMBL14007030 0.79 ALDH1A1 (0.55) ALDH1A1RAB9ANPC1AGTR2MEN1
SCHEMBL27326668 0.75 ALDH1A1 (0.41) ALDH1A1AGTR2MEN1KMT2AATM
SCHEMBL5128683 0.75 ALDH1A1 (0.51) ALDH1A1RAB9ANPC1AGTR2MEN1
SCHEMBL7663892 0.75 KMT2A (0.40) ALDH1A1RAB9ANPC1MEN1KMT2A
SCHEMBL7669094 0.73 ALDH1A1 (0.39) ALDH1A1AGTR2MAPTL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed