Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668164 | 0.89 | MAPT (0.41) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7671817 | 0.84 | MAPT (0.40) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL13513193 | 0.83 | ALDH1A1 (0.39) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7661985 | 0.83 | ALDH1A1 (0.42) | MAPTMAPK1ALDH1A1KDM4EALDH2 | |
| SCHEMBL7657370 | 0.82 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL13040227 | 0.82 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7668713 | 0.79 | GAA (0.41) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL876587 | 0.79 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7636271 | 0.77 | CHRNB2 (0.38) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7636265 | 0.77 | CHRNB2 (0.38) | MAPTALDH1A1KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |