Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040227 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL14646127 | 0.82 | MEN1 (0.35) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL13822120 | 0.82 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| Nitenpyram SCHEMBL25789 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1MAPTFAAHCHRNA1CHRNB2 | |
| Nitenpyram SCHEMBL29388004 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1MAPTFAAHCHRNA1CHRNB2 | |
| Nitenpyram SCHEMBL13448342 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1MAPTFAAHCHRNA1CHRNB2 | |
| Nitenpyram SCHEMBL25788 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1MAPTFAAHCHRNA1CHRNB2 | |
| Nitenpyram SCHEMBL31030931 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1MAPTFAAHCHRNA1CHRNB2 | |
| Nitenpyram SCHEMBL28400760 | 0.79 | SMN1; SMN2 (0.39) | ALDH1A1MAPTFAAHNPC1RAB9A | |
| SCHEMBL8401753 | 0.79 | MAPT (0.43) | ALDH1A1KDM4EGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143192-B2 | Methods for increasing the resistance of plants to hypoxic conditions | BAYER CROPSCIENCE N.V. (BE) | 2012-03-27 | — | — | US | disclosed |
| WO-2012017971-A1 | PEST CONTROL COMPOSITION | 住友化学株式会社 (JP) | 2012-02-09 | — | — | WO | disclosed |
| US-20100291022-A1 | Fly Gel Bait | BAYER CROPSCIENCE AG (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20090270254-A1 | Increase of stress tolerance by application of neonicotinoids on plants engineered to be stress tolerant | BAYER CROPSCIENCE AG (DE) | 2009-10-29 | — | — | US | disclosed |
| US-20090064371-A1 | Methods for Increasing the Resistance of Plants to Hypoxic Conditions | BAYER BIOSCIENCE N.V. (BE) | 2009-03-05 | — | — | US | disclosed |
| US-20080261810-A1 | Insecticides Based on Neonicotinoids and Safeners | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080089857-A1 | Fly Gel Bait | BAYER CROPSICIENCE LP (US) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261810-A1 | Insecticides Based on Neonicotinoids and Safeners | CYP4X1, PRDX4, PRDX1 | ALDH1A1 3269/4885KDM4E 4060/4885GAA 2711/4885 |
| US-20100291022-A1 | Fly Gel Bait | MSN, WAPL, ARFGEF1 | ALDH1A1 4705/4885KDM4E 2669/4885GAA 4108/4885 |
| US-20080089857-A1 | Fly Gel Bait | MSN, WAPL, ARFGEF1 | ALDH1A1 4748/4885KDM4E 2661/4885GAA 4203/4885 |
| US-20090270254-A1 | Increase of stress tolerance by application of neonicotinoids on plants engineered to be stress tolerant | CDA, NAPRT, NIT2 | ALDH1A1 664/4885KDM4E 3262/4885GAA 1181/4885 |
| US-20090064371-A1 | Methods for Increasing the Resistance of Plants to Hypoxic Conditions | COXFA4L2, HIF1A, HYOU1 | ALDH1A1 1125/4885KDM4E 1812/4885GAA 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.