Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL1389386 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL3912160 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL15225 | 0.87 | — | — | |
| SCHEMBL6247615 | 0.87 | CARM1 (0.37) | ALDH1A1TSHRPRMT3CARM1PRMT6 | |
| SCHEMBL16561236 | 0.86 | CA12 (0.53) | ALDH1A1TSHRMEN1CA12CA6 | |
| SCHEMBL10976565 | 0.84 | CA12 (0.50) | ALDH1A1TSHRMEN1CA12CA6 | |
| Water SCHEMBL2274846 | 0.83 | PRMT3 (0.35) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Ammonia Solution, Strong SCHEMBL10620957 | 0.83 | — | — | |
| Bromide SCHEMBL437925 | 0.83 | — | — | |
| SCHEMBL29936682 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754565-B1 | A concentrated dampening solution with an improved anti-staining activity for printing with a lithographic printing plate obtained according to the silver salt diffusion transfer process | AGFA GEVAERT NV (BE) | 1999-06-16 | — | — | EP | disclosed |
| EP-0754565-A1 | A concentrated dampening solution with an improved anti-staining activity for printing with a lithographic printing plate obtained according to the silver salt diffusion transfer process | AGFA-GEVAERT N.V. (BE) | 1997-01-22 | — | — | EP | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |