Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbon Tetrachloride SCHEMBL7586209 | 0.95 | LMNA (0.36) | TSHRLMNAALDH1A1CYP2E1THRB | |
| Chloroform SCHEMBL28176439 | 0.89 | — | — | |
| Chloroform SCHEMBL5747359 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL2571706 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL9037829 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL9526391 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL48119 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL9525441 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL9568279 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 | |
| Chloroform SCHEMBL888275 | 0.84 | LMNA (0.57) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923594-A1 | BROMOTIACUMICIN COMPOUNDS | Abbott Laboratories (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998002447-A1 | BROMOTIACUMICIN COMPOUNDS | ABBOTT LABORATORIES (US) | 1998-01-22 | — | — | WO | disclosed |