Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353946 | 0.82 | NR4A1 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7356370 | 0.78 | RAB9A (0.49) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL9057293 | 0.77 | ALDH1A1 (0.96) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL29687907 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL116566 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL27144 | 0.74 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL3424984 | 0.74 | ALDH1A1 (0.96) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7348109 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| Benzyl Benzoate SCHEMBL10973774 | 0.72 | TDP1 (0.82) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| Ethylene Glycol SCHEMBL11543264 | 0.71 | ALDH1A1 (0.90) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |