Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654456 | 0.82 | NR4A1 (0.51) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL3993457 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7399817 | 0.78 | RAB9A (0.49) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL2185619 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL5045569 | 0.77 | LMNA (0.45) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6645697 | 0.77 | LMNA (0.45) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6645702 | 0.77 | LMNA (0.45) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL5177381 | 0.77 | LMNA (0.45) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7404735 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7346308 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741804-A | Substituted benzimazoles which inhibit platelet aggrecation | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0672034-A4 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION. | SMITHKLINE BEECHAM CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0672034-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012478-A1 | BENZIMIDAZOLE COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION | SMITHKLINE BEECHAM CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |