SCHEMBL840303

SCHEMBL840303

CCC(O)(C(=O)O)C1(C#N)CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CTSK P43235 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31
CACNA2D1 P54289 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11057627 0.69
Hydrochloric Acid SCHEMBL841672 0.69 USP2 (0.38) ADORA3ALDH1A1USP2LMNACYP1A2
SCHEMBL2864827 0.69 ALDH1A1 (0.42) ALDH1A1
SCHEMBL20465359 0.67 FFAR3 (0.33) ALDH1A1TSHR
SCHEMBL3816278 0.65 ADORA3 (0.33) ADORA3
SCHEMBL4968787 0.64 ALDH1A1 (0.40) ALDH1A1
Acetic Acid SCHEMBL9843655 0.63 ALDH1A1 (0.37) ALDH1A1CTSKUSP2LMNACYP1A2
SCHEMBL841368 0.62 ALDH1A1 (0.31) ALDH1A1
SCHEMBL28959862 0.61 ALDH1A1 (0.37) ALDH1A1
SCHEMBL11272259 0.61 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143443-B2 Process for preparing gabapentin ZACH SYSTEM S.P.A. (IT) 2012-03-27 US disclosed