SCHEMBL8403199

SCHEMBL8403199

Cc1ccc2c(c1)N(CC(N)=O)C(=O)C(N(C(N)=O)c1cccc(-c3nnn[nH]3)c1)CC2C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 11/20 0.42
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8399465 0.90 CCKBR (0.43) CCKBR
SCHEMBL8402207 0.88 CCKBR (0.39) CCKBR
SCHEMBL8917130 0.88 CCKBR (0.41) CCKBR
SCHEMBL8398988 0.86 CCKBR (0.41) CCKBR
SCHEMBL8398505 0.86 CCKBR (0.41) CCKBR
SCHEMBL8398474 0.85 CCKBR (0.34) CCKBRLMNANPSR1
SCHEMBL8401331 0.84 CCKBR (0.42) CCKBRLMNANPSR1
SCHEMBL8399432 0.83 CCKBR (0.51) CCKBRNPSR1
SCHEMBL8913795 0.82 CCKBR (0.51) CCKBRNPSR1
Potassium Ion SCHEMBL8400982 0.82 CCKBR (0.43) CCKBRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711283-B1 TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS PFIZER (US) 1999-06-16 EP disclosed