Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Perchlorate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL6336257 | 0.86 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL686396 | 0.82 | — | — | |
| Nitric Acid SCHEMBL3779829 | 0.78 | CA5A (0.40) | NOS3NOS1NOS2 | |
| Perchlorate SCHEMBL8404022 | 0.71 | — | — | |
| Furan SCHEMBL27850549 | 0.68 | IDO1 (0.32) | — | |
| SCHEMBL20268967 | 0.65 | — | — | |
| Perchlorate SCHEMBL3218815 | 0.65 | CA5A (0.47) | — | |
| Perchlorate SCHEMBL8007282 | 0.65 | CA5A (0.47) | — | |
| Perchlorate SCHEMBL7047360 | 0.65 | — | — | |
| Perchlorate SCHEMBL8404059 | 0.65 | CA5A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922015-A1 | GAS GENERATING COMPOSITIONS | Talley Defence Systems, Incorporated (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5780768-A | Gas generating compositions | TALLEY DEFENSE SYSTEMS, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998008782-A1 | GAS GENERATING COMPOSITIONS | TALLEY DEFENSE SYSTEMS, INC. (US) | 1998-03-05 | — | — | WO | disclosed |