Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686396 | 0.95 | — | — | |
| Perchlorate SCHEMBL6336257 | 0.82 | NOS3 (0.30) | IDO1NOS3NOS1NOS2 | |
| Nitric Acid SCHEMBL332649 | 0.81 | CA5A (0.47) | CA5ACA5BNOS3NOS1NOS2 | |
| Nitric Acid SCHEMBL7461340 | 0.81 | CA5A (0.47) | CA5ACA5BNOS3NOS1NOS2 | |
| Furan SCHEMBL27850549 | 0.79 | IDO1 (0.32) | IDO1 | |
| Perchlorate SCHEMBL8403264 | 0.78 | NOS3 (0.34) | NOS3NOS1NOS2 | |
| Guanidine SCHEMBL6384671 | 0.74 | CA5A (0.61) | CA5ACA5BIDO1 | |
| Guanidine SCHEMBL742686 | 0.74 | CA5A (0.61) | CA5ACA5BIDO1 | |
| Guanidine SCHEMBL1013287 | 0.74 | CA5A (0.61) | CA5ACA5BIDO1 | |
| Guanidine SCHEMBL11252247 | 0.74 | CA5A (0.61) | CA5ACA5BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102173973-A | Igniter for gas generator of safety gasbag and preparation method thereof | SHANGHAI EAST JOY LONG MOTOR AIRBAG CO LTD | 2011-09-07 | — | — | CN | claimed |
| CN-100465097-C | Basic metal nitrate, method for producing the same and gas-generating agent composition | DAICEL CHEM (JP) | 2009-03-04 | — | — | CN | claimed |
| CN-1651360-A | Gas producing composition and its preparation method | ZHANG GENFA (CN) | 2005-08-10 | — | — | CN | claimed |
| US-8613821-B2 | Basic metal nitrate, process for producing the same and gas generating agent composition | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2013-12-24 | — | — | US | disclosed |
| CN-102173973-B | Igniter for gas generator of safety gasbag and preparation method thereof | SHANGHAI EAST JOY LONG MOTOR AIRBAG CO LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-102173973-A | Igniter for gas generator of safety gasbag and preparation method thereof | SHANGHAI EAST JOY LONG MOTOR AIRBAG CO LTD | 2011-09-07 | — | — | CN | disclosed |
| US-20100326574-A1 | BASIC METAL NITRATE, PROCESS FOR PRODUCING THE SAME AND GAS GENERATING AGENT COMPOSITION | ZHOU XINGXI | 2010-12-30 | — | — | US | disclosed |
| US-20090101250-A1 | BASIC METAL NITRATE, PROCESS FOR PRODUCING THE SAME AND GAS GENERATING AGENT COMPOSITION | ZHOU XINGXI | 2009-04-23 | — | — | US | disclosed |
| CN-100465097-C | Basic metal nitrate, method for producing the same and gas-generating agent composition | DAICEL CHEM (JP) | 2009-03-04 | — | — | CN | disclosed |
| CN-100376515-C | Gas producing composition and its preparation method | EAST JIULE AUTOMOBILE SAFETY A (CN) | 2008-03-26 | — | — | CN | disclosed |
| CN-1651360-A | Gas producing composition and its preparation method | ZHANG GENFA (CN) | 2005-08-10 | — | — | CN | disclosed |
| CN-1416410-A | Gas generator with automatic firing function | DAICEL CHEMICAL INDNSTRIES LTD (JP) | 2003-05-07 | — | — | CN | disclosed |