SCHEMBL8403752

SCHEMBL8403752

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(I)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.35
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4020407 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL1727233 0.96 LMNA (0.44) LMNATHRBCA2
SCHEMBL10704651 0.96 LMNA (0.44) LMNATHRBCA2
SCHEMBL815129 0.96 LMNA (0.37) LMNATHRB
SCHEMBL7574573 0.87 LMNA (0.38) LMNATHRB
SCHEMBL2553767 0.86 LMNA (0.42) LMNATHRBCA2
SCHEMBL3230572 0.86 LMNA (0.42) LMNATHRBCA2
SCHEMBL534458 0.86 LMNA (0.42) LMNATHRBCA2
SCHEMBL4889172 0.86 LMNA (0.42) LMNATHRBCA2
SCHEMBL10341441 0.86 LMNA (0.42) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801491-A Polycarbonate composition and preparation method and application thereof 万华化学集团股份有限公司 2024-04-02 CN disclosed
US-5929293-A Process for the preparation of fluoroolefins E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-27 US disclosed
WO-1997002226-A1 PROCESS FOR THE PREPARATION OF FLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-23 WO disclosed