SCHEMBL534458

SCHEMBL534458

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(I)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.35
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28626157 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL28626623 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL28597248 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL28629013 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL10341441 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL3230572 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL4889172 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL28357131 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL2553767 1.00 LMNA (0.42) LMNATHRBCA2
SCHEMBL28596246 0.96 LMNA (0.37) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118079810-A Continuous preparation device and method for fluorine-containing olefin 浙江巨化技术中心有限公司 2024-05-28 CN claimed
CN-113388243-B Antibacterial polycarbonate and preparation method and application thereof 华南理工大学 2022-03-29 CN claimed
CN-114105727-A Preparation method of perfluoroalkyl ethylene 中昊晨光化工研究院有限公司 2022-03-01 CN claimed
CN-113388243-A Antibacterial polycarbonate and preparation method and application thereof 华南理工大学 2021-09-14 CN claimed
CN-114874783-B Fluorine-containing surfactant, application thereof, preparation method thereof and fire extinguishing agent formed by fluorine-containing surfactant 浙江睦田消防科技开发有限公司 2024-07-02 CN disclosed
CN-118079810-A Continuous preparation device and method for fluorine-containing olefin 浙江巨化技术中心有限公司 2024-05-28 CN disclosed
CN-116555766-A Corrosion inhibitor for cooling liquid, preparation method of corrosion inhibitor and cooling liquid 深圳市英维克科技股份有限公司 2023-08-08 CN disclosed
CN-115093307-A Perfluoroalkyl ethylene, continuous preparation method and continuous production equipment thereof 福建三农新材料有限责任公司 2022-09-23 CN disclosed
CN-114874783-A Fluorine-containing surfactant, application and preparation method thereof, and fire extinguishing agent comprising fluorine-containing surfactant 浙江睦田消防科技开发有限公司 2022-08-09 CN disclosed
CN-109996832-B Polymer, composition and molded article 大金工业株式会社 2022-07-01 CN disclosed
CN-113388243-B Antibacterial polycarbonate and preparation method and application thereof 华南理工大学 2022-03-29 CN disclosed
CN-113388243-A Antibacterial polycarbonate and preparation method and application thereof 华南理工大学 2021-09-14 CN disclosed
EP-1309530-B1 PROCESS FOR DEHYDROHALOGENATION OF HALOGENATED COMPOUNDS DUPONT DOW ELASTOMERS LLC (US) 2006-07-26 EP disclosed
US-6620972-B2 Fluorous sulfoxides used to oxidize primary or secondary alcohols to aldehydes or ketones in presence of activator, followed by treatment with organic base THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-09-16 US disclosed
US-20030105363-A1 Method of oxidizing an alcohol using a recyclable fluorous sulfoxide UNIVERSITY OF ILLINOIS AT CHICAGO 2003-06-05 US disclosed
EP-1309530-A2 PROCESS FOR DEHYDROHALOGENATION OF HALOGENATED COMPOUNDS DUPONT DOW ELASTOMERS L.L.C. (US) 2003-05-14 EP disclosed
WO-2003002526-A1 METHOD OF OXIDIZING AN ALCOHOL USING A RECYCLABLE FLUOROUS SULFOXIDE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-01-09 WO disclosed
US-6380446-B1 Process for dehydrohalogenation of halogenated compounds DUPONT DOW ELASTOMERS, L.L.C. 2002-04-30 US disclosed
WO-2002014247-A2 PROCESS FOR DEHYDROHALOGENATION OF HALOGENATED COMPOUNDS DUPONT DOW ELASTOMERS L.L.C. (US) 2002-02-21 WO disclosed
US-20020022753-A1 PROCESS FOR DEHYDROHALOGENATION OF HALOG ENATED COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY 2002-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105363-A1 Method of oxidizing an alcohol using a recyclable fluorous sulfoxide AOX1, SMOX, ADH1A LMNA 4796/4885THRB 1478/4885CA2 4449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.