SCHEMBL815129

SCHEMBL815129

FC(F)(F)C(F)(F)C(F)(F)C(F)(I)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8403752 0.96 LMNA (0.42) LMNATHRB
SCHEMBL4020407 0.96 LMNA (0.42) LMNATHRB
SCHEMBL10704651 0.92 LMNA (0.44) LMNATHRB
SCHEMBL1727233 0.92 LMNA (0.44) LMNATHRB
SCHEMBL7574573 0.83 LMNA (0.38) LMNATHRB
SCHEMBL3230572 0.81 LMNA (0.42) LMNATHRB
SCHEMBL2553767 0.81 LMNA (0.42) LMNATHRB
SCHEMBL4889172 0.81 LMNA (0.42) LMNATHRB
SCHEMBL10341441 0.81 LMNA (0.42) LMNATHRB
SCHEMBL534458 0.81 LMNA (0.42) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012012804-A3 DEVICES FOR SECURING A JUNIOR GOLF BAG TO A GOLF CART AND METHODS OF USE THEREOF MIZE FREDY (US) 2012-05-10 WO disclosed
EP-2173703-B1 FLUOROALKYL SURFACTANTS DU PONT (US) 2011-11-30 EP disclosed
US-8058375-B2 Use of ethylene-tetrafluoroethylene carboxylic acids and salts as surfactants for aqueous emulsion polymerization of fluorinated monomer E I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-15 US disclosed
EP-2370392-A1 ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
WO-2010075354-A1 ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
US-20100160584-A1 Ethylene-Tetrafluoroethylene Carboxylic Acids and Salts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed
US-20100160550-A1 USE OF ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS AS SURFACTANTS FOR AQUEOUS EMULSION POLYMERIZATION OF FLUORINATED MONOMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed
EP-2173703-A1 FLUOROALKYL SURFACTANTS E. I. du Pont de Nemours and Company (US) 2010-04-14 EP disclosed
US-7638650-B2 Fluoroalkyl surfactants E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-29 US disclosed
WO-2009020910-A1 FLUOROALKYL SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-12 WO disclosed
US-20090043130-A1 Fluoroalkyl surfactants E. I. DU PONT DE NEMOURS AND COMPANY 2009-02-12 US disclosed
EP-0252736-A2 Process for preparing fluorine-containing carboxylic acid ester SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043130-A1 Fluoroalkyl surfactants CBR1, CBR3, NHERF1 LMNA 1392/4885THRB 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.