Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ATP4A | P20648 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401940 | 0.89 | ACHE (0.31) | MAPTMEN1LMNAKMT2AACHE | |
| SCHEMBL8401724 | 0.87 | RECQL (0.36) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL8401739 | 0.86 | RECQL (0.36) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL7660109 | 0.85 | RECQL (0.38) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL7683790 | 0.85 | RECQL (0.38) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL8405315 | 0.83 | RECQL (0.36) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL8401700 | 0.78 | RECQL (0.36) | RECQLMAPTPOLBGAAKDM4E | |
| SCHEMBL7670572 | 0.78 | RECQL (0.35) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL7662516 | 0.77 | MAPT (0.39) | RECQLMAPTPOLBGAABMP1 | |
| SCHEMBL7666642 | 0.76 | RECQL (0.38) | RECQLMAPTPOLBGAABMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |