SCHEMBL7683790

SCHEMBL7683790

CN/C(=C\[N+](=O)[O-])N(C)Cc1cnc(Cl)s1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.38
MAPT P10636 3/20 0.37
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
BMP1 P13497 1/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
LMNA P02545 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
ACHE P22303 2/20 0.33
SLC22A1 O15245 1/20 0.33
ABCB11 O95342 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
TSHR P16473 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
ATP4A P20648 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7660109 1.00 RECQL (0.38) RECQLMAPTPOLBGAABMP1
SCHEMBL8401724 0.88 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL8405315 0.88 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL7664952 0.88 ACHE (0.33) MAPTKMT2AMEN1LMNAACHE
SCHEMBL7662478 0.85 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL236049 0.85 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL236048 0.85 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL7668954 0.85 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL7679007 0.85 RECQL (0.36) RECQLMAPTPOLBGAABMP1
SCHEMBL8404109 0.85 RECQL (0.35) RECQLMAPTPOLBGAABMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500416-B2 FLUID FLOW; INSECTICIDE; MITICIDE SYNGENTA CROP PROTECTION, INC. 2002-12-31 US disclosed
US-20010021378-A1 Pesticide SYNGENTA CROP PROTECTION, INC. 2001-09-13 US disclosed
EP-0909130-A1 PESTICIDE Novartis AG (CH) 1999-04-21 EP disclosed
WO-1997042815-A1 PESTICIDE NOVARTIS AG (CH) 1997-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010021378-A1 Pesticide DDT, KISS1R, ACHE RECQL 1520/4885MAPT 1014/4885POLB 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.