Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27549934 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL30115183 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL26658 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL4915829 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL305295 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL10690535 | 0.82 | HTT (0.45) | ALDH1A1L3MBTL1RAB9AGAAMAPT | |
| SCHEMBL31228371 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL27818032 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL16370038 | 0.81 | HTT (0.43) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 | |
| SCHEMBL5245374 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2ATDP1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1277819-C | Process for producing azetidinone compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2006-10-04 | — | — | CN | disclosed |
| CN-1610663-A | Process for producing azetidinone compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2005-04-27 | — | — | CN | disclosed |
| US-5998612-A | Antibiotic synthesis | MERCK SHARP & DOHME CORP. | 1999-12-07 | — | — | US | disclosed |
| EP-0078026-B1 | ANTIBIOTIC SYNTHESIS | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0078026-A2 | Antibiotic synthesis | MERCK & CO. INC. (US) | 1983-05-04 | — | — | EP | disclosed |