Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.47 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785167 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL24910475 | 0.85 | L3MBTL1 (0.43) | SMN1; SMN2ALDH1A1MAPTKDM4EESR1 | |
| SCHEMBL10833303 | 0.84 | GAA (0.36) | SMN1; SMN2ALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL10784863 | 0.76 | L3MBTL1 (0.35) | SMN1; SMN2ALDH1A1MAPTKDM4EESR1 | |
| SCHEMBL14431307 | 0.75 | GAA (0.41) | SMN1; SMN2ALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL2756560 | 0.74 | L3MBTL1 (0.53) | SMN1; SMN2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL11041469 | 0.74 | CHRNB2 (0.46) | SMN1; SMN2ALDH1A1ALOX15MAPTKDM4E | |
| SCHEMBL9912823 | 0.72 | L3MBTL1 (0.52) | SMN1; SMN2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL10784868 | 0.72 | CNR2 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL22323880 | 0.71 | ESR1 (0.50) | SMN1; SMN2ALDH1A1ALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11043484-A | — | — | None | — | — | JP | disclosed |
| JP-56100771-A | — | — | None | — | — | JP | disclosed |
| JP-H1143484-A | PRODUCTION OF 6-ALKYLOXY-5-TERTIARY-BUTYL-2-METHYL-BENZOXAZOLE | SUMIKA FINE CHEM KK | 1999-02-16 | — | — | JP | disclosed |
| US-4594426-A | Benzoxazole derivative intermediates for synthesis of dye releasing redox compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| JP-S56100771-A | BENZOXAZOLE DERIVATIVE | FUJI PHOTO FILM CO LTD | 1981-08-12 | — | — | JP | disclosed |