Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404540 | 1.00 | L3MBTL1 (0.37) | L3MBTL1KDM1AKDM1BAGTR1ALDH1A1 | |
| SCHEMBL8404745 | 0.87 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1PTGS2CCR2 | |
| SCHEMBL8404554 | 0.87 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1POLBLMNATSHR | |
| SCHEMBL8408242 | 0.86 | KDM1A (0.40) | KDM1AKDM1BALDH1A1PTGS2LMNA | |
| SCHEMBL8404542 | 0.86 | KDM1A (0.40) | KDM1AKDM1BALDH1A1PTGS2LMNA | |
| SCHEMBL2597082 | 0.85 | L3MBTL1 (0.41) | L3MBTL1KDM1AKDM1BAGTR1ALDH1A1 | |
| SCHEMBL8404747 | 0.79 | PTGS2 (0.37) | L3MBTL1AGTR1ALDH1A1PTGS2CCR2 | |
| SCHEMBL8404543 | 0.79 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1POLBLMNATSHR | |
| SCHEMBL8404549 | 0.79 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1POLBLMNATSHR | |
| SCHEMBL8404545 | 0.79 | PTGS2 (0.37) | L3MBTL1AGTR1ALDH1A1PTGS2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |