Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ATP4A | P20648 | 1/20 | 0.56 |
| ▸ | ATP4B | P51164 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408366 | 0.88 | ATP4A (0.73) | ATP4AATP4B | |
| SCHEMBL8569446 | 0.87 | ATP4A (0.55) | ATP4AATP4B | |
| SCHEMBL11250615 | 0.85 | TP53 (0.66) | TP53MAPTATP4AATP4BTHRB | |
| SCHEMBL7847409 | 0.84 | ATP4A (0.78) | ATP4AATP4B | |
| Hydrochloric Acid SCHEMBL11246958 | 0.84 | TP53 (0.65) | TP53MAPTATP4AATP4BTHRB | |
| Hydrochloric Acid SCHEMBL11233459 | 0.84 | ATP4A (0.76) | ATP4AATP4B | |
| SCHEMBL7848455 | 0.82 | TP53 (0.71) | TP53MAPTATP4AATP4BTHRB | |
| SCHEMBL8405322 | 0.82 | MAPT (0.52) | TP53MAPTATP4AATP4BTHRB | |
| SCHEMBL8405251 | 0.82 | ATP4A (0.67) | ATP4AATP4B | |
| SCHEMBL11233814 | 0.81 | THRB (0.68) | ATP4AATP4BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952504-A | REACTING A SULFONATED, HALOGENATED OR PHOSPHONATED 1,7-NAPHTHYRIDINE COMPOUNDS WITH AN AROMATIC AMINE DERIVATIVE; ANTIULCER AGENT | YUNGJIN PHARMACEUTICAL COMPANY, LTD. (KR) | 1999-09-14 | — | — | US | disclosed |
| EP-0843677-A1 | 4-AMINO-3-ACYLNAPHTHYRIDINE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003074-A1 | 4-AMINO-3-ACYLNAPHTHYRIDINE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-01-30 | — | — | WO | disclosed |