SCHEMBL8405374

SCHEMBL8405374

CCN1CCC=C(c2cnoc2N)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL7425593 0.92 CHRM2 (0.38)
SCHEMBL7420354 0.81 CHRM2 (0.45)
Oxalic Acid SCHEMBL7421064 0.76 TDO2 (0.39)
Oxalic Acid SCHEMBL7424310 0.74 CHRM2 (0.53)
Oxalic Acid SCHEMBL7417869 0.72 CHRM2 (0.38)
SCHEMBL9451907 0.67 RECQL (0.40)
SCHEMBL9724689 0.67 CHRM2 (0.58)
Hydrochloric Acid SCHEMBL9724640 0.66 CHRM2 (0.56)
SCHEMBL8405951 0.64 CHRM2 (0.46)
SCHEMBL7419072 0.64 CHRM2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994373-A COGNITION ACTIVATORS; GASTROINTESTINAL DISORDERS; PSYCHOLOGICAL DISORDERS NOVO NORDISK A/S NOVO ALLE DK 2880 (DK) 1999-11-30 US disclosed